10.6084/m9.figshare.5739561.v1
Poomraphie Nuntawong
Poomraphie
Nuntawong
Virunh Kongkatitham
Virunh
Kongkatitham
Kittisak Likhitwitayawuid
Kittisak
Likhitwitayawuid
Wanwimon Mekboonsonglarp
Wanwimon
Mekboonsonglarp
Suchada Sukrong
Suchada
Sukrong
Somboon Tanasupawat
Somboon
Tanasupawat
Boonchoo Sritularak
Boonchoo
Sritularak
New 2-arylbenzofurans from the root bark of <i>Artocarpus gomezianus</i> and their α-glucosidase inhibitory activity
Taylor & Francis Group
2017
Artocarpus gomezianus
Moraceae
2-arylbenzofuran
α-glucosidase
2017-12-28 05:23:01
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/New_2-arylbenzofurans_from_the_root_bark_of_i_Artocarpus_gomezianus_i_and_their_-glucosidase_inhibitory_activity/5739561
<p>Two new 2-arylbenzofurans, namely 13-<i>O</i>-methyllakoochin B (<b>1</b>) and artogomezianin (<b>2</b>), were isolated from the root bark of <i>Artocarpus gomezianus</i>, along with six known compounds (<b>3</b>–<b>8</b>). The structures of new compounds were determined by spectroscopic and chemical methods. All of the isolates were evaluated for their α-glucosidase inhibitory activity. Artogomezianin (<b>2</b>) and lakoochin A (<b>3</b>) exhibited strong α-glucosidase inhibitory activity with IC<sub>50</sub> values of 18.25 and 26.19 µM, respectively, as compared with the positive control acarbose.</p>