TY - DATA T1 - FAST SIMULTANEOUS DETERMINATION OF PROPIFENAZONE, PARACETAMOL AND CAFFEINE USING BATCH INJECTION ANALYSIS WITH AMPEROMETRIC DETECTION PY - 2017/12/27 AU - Weberson Pereira Silva AU - Luiz André Juvêncio Silva AU - Rodrigo Alejandro Abarza Muñoz AU - Eduardo Mathias Richter UR - https://scielo.figshare.com/articles/dataset/FAST_SIMULTANEOUS_DETERMINATION_OF_PROPIFENAZONE_PARACETAMOL_AND_CAFFEINE_USING_BATCH_INJECTION_ANALYSIS_WITH_AMPEROMETRIC_DETECTION/5734503 DO - 10.6084/m9.figshare.5734503.v1 L4 - https://ndownloader.figshare.com/files/10092831 L4 - https://ndownloader.figshare.com/files/10092837 L4 - https://ndownloader.figshare.com/files/10092843 L4 - https://ndownloader.figshare.com/files/10092849 L4 - https://ndownloader.figshare.com/files/10092852 L4 - https://ndownloader.figshare.com/files/10092861 L4 - https://ndownloader.figshare.com/files/10092867 KW - boron doped diamond electrode (BDDE) KW - multiple-pulse amperometric detection KW - portable electrochemical method KW - pharmaceutical N2 - A fast and simple procedure for simultaneous determination of propyphenazone (PRO), paracetamol (PAR) and caffeine (CAF) was performed using batch injection analysis with multiple pulse amperometric detection (BIA-MPA). Three potentials pulses were selected for the analysis: +0.90 V/50 ms: only PAR was oxidized; +1.20 V/50 ms: oxidation of PAR and PRO without the interference of CAF; +1.60 V/50 ms: oxidation of the three compounds (PAR, PRO and CAF). The sample aliquot (150 µL) was directly injected onto the boron-doped diamond (BDD) electrode immersed in a BIA cell. The analytical characteristics of the proposed method include high analytical frequency (75 injections per hour), good stability (RSD < 3.9%; n = 10), and low detection limits (0.3, 0.2 and 0.1 mg L−1 for PRO, PAR and CAF, respectively). The proposed method yielded similar results to those obtained by liquid chromatography at a 95% confidence level. ER -