TY - DATA T1 - Survival outcome among patients with Ewing’s sarcoma of bones and joints: a population-based cohort study PY - 2017/12/20 AU - Zi-Hao Wan AU - Zhi-Hao Huang AU - Liao-Bin Chen UR - https://scielo.figshare.com/articles/dataset/Survival_outcome_among_patients_with_Ewing_s_sarcoma_of_bones_and_joints_a_population-based_cohort_study/5720023 DO - 10.6084/m9.figshare.5720023.v1 L4 - https://ndownloader.figshare.com/files/10048666 L4 - https://ndownloader.figshare.com/files/10048672 L4 - https://ndownloader.figshare.com/files/10048678 L4 - https://ndownloader.figshare.com/files/10048684 L4 - https://ndownloader.figshare.com/files/10048690 L4 - https://ndownloader.figshare.com/files/10048699 L4 - https://ndownloader.figshare.com/files/10048711 KW - Bone and bones KW - Sarcoma, Ewing KW - Survival analysis KW - Retrospective studies N2 - ABSTRACT BACKGROUND: The aim here was to elucidate the current survival condition of patients diagnosed with Ewing’s sarcoma of the bones and joints and determine independent risk factors associated with the prognosis. DESIGN AND SETTING: Retrospective cohort study based on the Surveillance, Epidemiology and End Results (SEER) database in the United States. METHODS: We identified 397 patients who were diagnosed with Ewing’s sarcoma of the bones and joints between January 2004 and December 2013. The multivariate Cox proportional hazards model was used to determine factors associated with the risk of death by adjusting for various factors. RESULTS: The one, two and five-year disease-specific survival rates were 89.08%, 78.08% and 62.47%, respectively. The factors related to death were age (≥ 18 years versus < 18 years; hazard ratio, HR = 1.77; 95% confidence interval, CI: 1.38-2.31); tumor site (extremity versus spine and pelvis; HR = 2.03; 95% CI: 1.31-2.62); tumor size (> 10 cm versus ≤ 10 cm; HR = 1.78; 95% CI: 1.34-2.56); and type of treatment (surgery alone versus radiotherapy with surgery; HR = 0.51; 95% CI: 0.38-0.89; or radiotherapy alone versus radiotherapy with surgery; HR = 1.61; 95% CI: 1.10-2.39; or no treatment versus radiotherapy with surgery; HR = 1.86; 95% CI: 1.23, 2.58). CONCLUSIONS: Patients with Ewing’s sarcoma showed poor survival in situations of age ≥ 18 years, tumor size > 10 cm, receiving radiotherapy alone and receiving no treatment. Patients undergoing surgery alone had better survival. ER -