TY - DATA T1 - Effectiveness of preoperative decolonization with nasal povidone iodine in Chinese patients undergoing elective orthopedic surgery: a prospective cross-sectional study PY - 2017/12/20 AU - H-M. Peng AU - L-C. Wang AU - J-L. Zhai AU - X-S. Weng AU - B. Feng AU - W. Wang UR - https://scielo.figshare.com/articles/dataset/Effectiveness_of_preoperative_decolonization_with_nasal_povidone_iodine_in_Chinese_patients_undergoing_elective_orthopedic_surgery_a_prospective_cross-sectional_study/5718862 DO - 10.6084/m9.figshare.5718862.v1 L4 - https://ndownloader.figshare.com/files/10041898 L4 - https://ndownloader.figshare.com/files/10041910 L4 - https://ndownloader.figshare.com/files/10041913 L4 - https://ndownloader.figshare.com/files/10041919 KW - Nasal methicillin-resistant KW - Staphylococcus aureus KW - Orthopedic surgery KW - Nasal povidone iodine KW - Prospective cross-sectional study N2 - Staphylococcus aureus colonization in the nares of patients undergoing elective orthopedic surgery increases the potential risk of surgical site infections. Methicillin-resistant S. aureus (MRSA) has gained recognition as a pathogen that is no longer only just a hospital-acquired pathogen. Patients positive for MRSA are associated with higher rates of morbidity and mortality following infection. MRSA is commonly found in the nares, and methicillin-sensitive S. aureus (MSSA) is even more prevalent. Recently, studies have determined that screening for this pathogen prior to surgery and diminishing staphylococcal infections at the surgical site will dramatically reduce surgical site infections. A nasal mupirocin treatment is shown to significantly reduce the colonization of the pathogen. However, this treatment is expensive and is currently not available in China. Thus, in this study, we first sought to determine the prevalence of MSSA/MSRA in patients undergoing elective orthopedic surgery in northern China, and then, we treated the positive patients with a nasal povidone-iodine swab. Here, we demonstrate a successful reduction in the colonization of S. aureus. We propose that this treatment could serve as a cost-effective means of eradicating this pathogen in patients undergoing elective orthopedic surgery, which might reduce the rate of surgical site infections. ER -