β<sup>low</sup>-cells have an altered cAMP signaling.
Melis Karaca
Julien Castel
Cécile Tourrel-Cuzin
Manuel Brun
Anne Géant
Mathilde Dubois
Sandra Catesson
Marianne Rodriguez
Serge Luquet
Pierre Cattan
Brian Lockhart
Jochen Lang
Alain Ktorza
Christophe Magnan
Catherine Kargar
10.1371/journal.pone.0005555.g004
https://plos.figshare.com/articles/figure/_low_cells_have_an_altered_cAMP_signaling_/568322
<p>Effects of 5.5 mM and 16.7 mM glucose±10 nM GLP-1 on insulin release (A) and cAMP content (B) in β<sup>high</sup> and β<sup>low</sup>-cells assessed by static incubation experiments (n = 3–5). (C) Effects of 5.5 mM and 16.7 mM glucose±5 mM db-cAMP on insulin secretion in β<sup>high</sup> and β<sup>low</sup>-cells (n = 3–5). n represents the number of independent cell preparations from 6 pooled rats each. Data are means±SEM. *, p<0.05 and **, p<0.01.</p>
2009-05-18 02:18:42
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