Benign familial fleck retina: multimodal imaging including optical coherence tomography angiography
Jose Mauricio Botto de Barros Garcia
David Leonardo Cruvinel Isaac
Tainara Sardeiro
Érika Aquino
Marcos Avila
10.6084/m9.figshare.5669164.v1
https://scielo.figshare.com/articles/dataset/Benign_familial_fleck_retina_multimodal_imaging_including_optical_coherence_tomography_angiography/5669164
<div><p>ABSTRACT This report presents multimodal imaging of a 27-year-old woman diagnosed with benign familial fleck retina (OMIM 228980), an uncommon disorder. Fundus photographs revealed retinal flecks that affected her post-equatorial retina but spared the macular area. Fundus autofluorescence and infrared imaging demonstrated a symmetrical pattern of yellow-white fleck lesions that affected both eyes. Her full-field electroretinogram and electrooculogram were normal. An optical coherence tomography B-scan was performed for both eyes, revealing increased thickness of the retinal pigmented epithelium leading to multiple small pigmented epithelium detachments. The outer retina remained intact in both eyes. Spectral-domain optical coherence tomography angiography with split-spectrum amplitude decorrelation algorithm and 3 × 3 mm structural en face optical coherence tomography did not show macular lesions. Benign familial fleck retina belongs to a heterogenous group of so-called flecked retina syndromes, and should be considered in patients with yellowish-white retinal lesions without involvement of the macula.</p></div>
2017-12-05 09:59:53
Eye diseases, hereditary/genetics
Eye diseases, hereditary/diagnosis
Retinal diseases/diagnosis
Retinal diseases/genetics
Tomography, optical coherence