10.6084/m9.figshare.5668327.v1 Laryssa Passos Sarmento Santos Laryssa Passos Sarmento Santos Victor Guerreiro Bomfim Victor Guerreiro Bomfim Camila Fagundes Bezerra Camila Fagundes Bezerra Natália Vieira Costa Natália Vieira Costa Rafael Barreto Paes de Carvalho Rafael Barreto Paes de Carvalho Ricardo Sobral de Carvalho Ricardo Sobral de Carvalho Rogério da Hora Passos Rogério da Hora Passos Olivia Carla Bomfim Boaventura Olivia Carla Bomfim Boaventura André Luiz Nunes Gobatto André Luiz Nunes Gobatto Heart conduction system defects and sustained ventricular tachycardia complications in a patient with granulomatosis with polyangiitis. A case report and literature review SciELO journals 2017 Granulomatosis with polyangiitis Atrioventricular block Heart conduction system Pacemaker, artificial Bradycardia Case reports 2017-12-05 09:32:45 Dataset https://scielo.figshare.com/articles/dataset/Heart_conduction_system_defects_and_sustained_ventricular_tachycardia_complications_in_a_patient_with_granulomatosis_with_polyangiitis_A_case_report_and_literature_review/5668327 <p></p><p>ABSTRACT Granulomatosis with polyangiitis is a rare systemic inflammatory disorder characterized by vasculitis of the small arteries, the arterioles and the capillaries together with necrotizing granulomatous lesions. This case reports on a young female patient, previously diagnosed with granulomatosis with polyangiitis, who was admitted to the intensive care unit with seizures and hemodynamic instability due to a complete atrioventricular heart block. The event was associated with multiple episodes of sustained ventricular tachycardia without any structural heart changes or electrolyte disturbances. In the intensive care unit, the patient was fitted with a provisory pacemaker, followed by immunosuppression with corticosteroids and immunobiological therapy, resulting in a total hemodynamic improvement. Severe conduction disorders in patients presenting granulomatosis with polyangiitis are rare but can contribute to increased morbidity. Early detection and specific intervention can prevent unfavorable outcomes, specifically in the intensive care unit.</p><p></p>