A new era of thromboelastometry
Tomaz Crochemore
Felipe Maia de Toledo Piza
Roseny dos Reis Rodrigues
João Carlos de Campos Guerra
Leonardo José Rolim Ferraz
Thiago Domingos Corrêa
10.6084/m9.figshare.5666884.v1
https://scielo.figshare.com/articles/dataset/A_new_era_of_thromboelastometry/5666884
<div><p>ABSTRACT Severe hemorrhage with necessity of allogeneic blood transfusion is common complication in intensive care unit and is associated with increased morbidity and mortality. Prompt recognition and treatment of bleeding causes becomes essential for the effective control of hemorrhage, rationalizing the use of allogeneic blood components, and in this way, preventing an occurrence of their potential adverse effects. Conventional coagulation tests such as prothrombin time and activated partial thromboplastin time present limitations in predicting bleeding and guiding transfusion therapy in critically ill patients. Viscoelastic tests such as thromboelastography and rotational thromboelastometry allow rapid detection of coagulopathy and goal-directed therapy with specific hemostatic drugs. The new era of thromboelastometry relies on its efficacy, practicality, reproducibility and cost-effectiveness to establish itself as the main diagnostic tool and transfusion guide in patients with severe active bleeding.</p></div>
2017-12-05 08:53:09
Hemorrhage/prevention & control
Blood transfusion/adverse effects
Goal-directed therapy
Thrombelastography/methods
Hemostatic drugs
Rotational thromboelastometry