%0 Journal Article %A Hu, Yue %A Jiao, Lin %A Jiang, Min-Hong %A Yin, Sheng %A Dong, Pan %A Zhao, Zhi-Min %A Yang, De-Po %A Ho, Pei-Tsai %A Wang, Dong-Mei %D 2017 %T A new C-glycosyl flavone and a new neolignan glycoside from Passiflora edulis Sims peel %U https://tandf.figshare.com/articles/journal_contribution/A_new_i_C_i_-glycosyl_flavone_and_a_new_neolignan_glycoside_from_i_Passiflora_edulis_i_Sims_peel/5662426 %R 10.6084/m9.figshare.5662426.v1 %2 https://ndownloader.figshare.com/files/9880522 %K Passiflora edulis Sims peel %K C-glycosyl flavone %K neolignan glycoside %X

A new C-glycosyl flavone, Chrysin-8-C-(2″-O-β-6-deoxy-glucopyranosyl)-β-D-glucopyranoside (1), a new neolignan glycoside, citrusin G (2), as well as 15 known compounds (317) were isolated from the peel of Passiflora edulis Sims. The structure determinations were primarily based on comprehensive spectroscopic analyses, and the absolute configuration of 2 were unequivocally determined by the CD experiment and chemical transformation. Compound 1 represents the rare examples of the flavonoid featuring a deoxy glucose sugar moiety. Compounds 5, 7 and 9 exhibited moderate inhibitory effects on nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells, with IC50 values of 34.92, 16.12 and 26.67 μM, respectively.

%I Taylor & Francis