Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome John K. Yue Ethan A. Winkler Sourabh Sharma Mary J. Vassar Jonathan J. Ratcliff Frederick K. Korley Seth A. Seabury Adam R. Ferguson Hester F. Lingsma Hansen Deng Sacha Meeuws Opeolu M. Adeoye Jonathan W. Rick Caitlin K. Robinson Siena M. Duarte Esther L. Yuh Pratik Mukherjee Sureyya S. Dikmen Thomas W. McAllister Ramon Diaz-Arrastia Alex B. Valadka Wayne A. Gordon David O. Okonkwo Geoffrey T. Manley 10.6084/m9.figshare.5627071.v2 https://tandf.figshare.com/articles/journal_contribution/Temporal_profile_of_care_following_mild_traumatic_brain_injury_predictors_of_hospital_admission_follow-up_referral_and_six-month_outcome/5627071 <p><i>Objective</i>: To investigate the clinical management and medical follow-up of patients with mild traumatic brain injury (mTBI) presenting to emergency departments (EDs). <i>Methods</i>: Overall, 168 adult patients with mTBI from the prospective, multicentre Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Pilot study with Glasgow Coma Scale (GCS) 13–15, no polytrauma and alive at six months were included. Predictors for hospital admission, three-month follow-up referral and six-month functional disability (Glasgow Outcome Scale-Extended (GOSE) ≤ 6) were analysed using multivariable regression. <i>Results</i>: Overall, 48% were admitted to hospital, 22% received three-month referral and 27% reported six-month functional disability. Intracranial pathology on ED head computed tomography (multivariable odds ratio (OR) = 81.08, 95% confidence interval (CI) [10.28–639.36]) and amnesia (>30-minutes: OR = 5.27 [1.75–15.87]; unknown duration: OR = 4.43 [1.26–15.62]) predicted hospital admission. Older age (per-year OR = 1.03 [1.01–1.05]) predicted three-month referral, while part-time/unemployment predicted lack of referral (OR = 0.17 [0.06–0.50]). GCS < 15 (OR = 2.46 [1.05–5.78]) and prior history of seizures (OR = 3.62 [1.21–10.89]) predicted six-month functional disability, while increased education (per-year OR = 0.86 [0.76–0.97]) was protective. <i>Conclusions</i>: Clinical factors modulate triage to admission, while demographic/socioeconomic elements modulate follow-up care acquisition; six-month functional disability associates with both clinical and demographic/socioeconomic variables. Improving triage to acute and outpatient care requires further investigation to optimize resource allocation and outcome after mTBI.</p> <p><b>ClinicalTrials.gov registration:</b> NCT01565551</p> 2018-09-10 16:36:47 Clinical evaluation follow-up care outcome assessment rehabilitation traumatic brain injury