10.6084/m9.figshare.5627071.v2 John K. Yue John K. Yue Ethan A. Winkler Ethan A. Winkler Sourabh Sharma Sourabh Sharma Mary J. Vassar Mary J. Vassar Jonathan J. Ratcliff Jonathan J. Ratcliff Frederick K. Korley Frederick K. Korley Seth A. Seabury Seth A. Seabury Adam R. Ferguson Adam R. Ferguson Hester F. Lingsma Hester F. Lingsma Hansen Deng Hansen Deng Sacha Meeuws Sacha Meeuws Opeolu M. Adeoye Opeolu M. Adeoye Jonathan W. Rick Jonathan W. Rick Caitlin K. Robinson Caitlin K. Robinson Siena M. Duarte Siena M. Duarte Esther L. Yuh Esther L. Yuh Pratik Mukherjee Pratik Mukherjee Sureyya S. Dikmen Sureyya S. Dikmen Thomas W. McAllister Thomas W. McAllister Ramon Diaz-Arrastia Ramon Diaz-Arrastia Alex B. Valadka Alex B. Valadka Wayne A. Gordon Wayne A. Gordon David O. Okonkwo David O. Okonkwo Geoffrey T. Manley Geoffrey T. Manley Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome Taylor & Francis Group 2018 Clinical evaluation follow-up care outcome assessment rehabilitation traumatic brain injury 2018-09-10 16:36:47 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Temporal_profile_of_care_following_mild_traumatic_brain_injury_predictors_of_hospital_admission_follow-up_referral_and_six-month_outcome/5627071 <p><i>Objective</i>: To investigate the clinical management and medical follow-up of patients with mild traumatic brain injury (mTBI) presenting to emergency departments (EDs). <i>Methods</i>: Overall, 168 adult patients with mTBI from the prospective, multicentre Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Pilot study with Glasgow Coma Scale (GCS) 13–15, no polytrauma and alive at six months were included. Predictors for hospital admission, three-month follow-up referral and six-month functional disability (Glasgow Outcome Scale-Extended (GOSE) ≤ 6) were analysed using multivariable regression. <i>Results</i>: Overall, 48% were admitted to hospital, 22% received three-month referral and 27% reported six-month functional disability. Intracranial pathology on ED head computed tomography (multivariable odds ratio (OR) = 81.08, 95% confidence interval (CI) [10.28–639.36]) and amnesia (>30-minutes: OR = 5.27 [1.75–15.87]; unknown duration: OR = 4.43 [1.26–15.62]) predicted hospital admission. Older age (per-year OR = 1.03 [1.01–1.05]) predicted three-month referral, while part-time/unemployment predicted lack of referral (OR = 0.17 [0.06–0.50]). GCS < 15 (OR = 2.46 [1.05–5.78]) and prior history of seizures (OR = 3.62 [1.21–10.89]) predicted six-month functional disability, while increased education (per-year OR = 0.86 [0.76–0.97]) was protective. <i>Conclusions</i>: Clinical factors modulate triage to admission, while demographic/socioeconomic elements modulate follow-up care acquisition; six-month functional disability associates with both clinical and demographic/socioeconomic variables. Improving triage to acute and outpatient care requires further investigation to optimize resource allocation and outcome after mTBI.</p> <p><b>ClinicalTrials.gov registration:</b> NCT01565551</p>