10.6084/m9.figshare.5627071.v2
John K. Yue
John K.
Yue
Ethan A. Winkler
Ethan A.
Winkler
Sourabh Sharma
Sourabh
Sharma
Mary J. Vassar
Mary J.
Vassar
Jonathan J. Ratcliff
Jonathan J.
Ratcliff
Frederick K. Korley
Frederick K.
Korley
Seth A. Seabury
Seth A.
Seabury
Adam R. Ferguson
Adam
R. Ferguson
Hester F. Lingsma
Hester
F. Lingsma
Hansen Deng
Hansen
Deng
Sacha Meeuws
Sacha
Meeuws
Opeolu M. Adeoye
Opeolu M.
Adeoye
Jonathan W. Rick
Jonathan W.
Rick
Caitlin K. Robinson
Caitlin K.
Robinson
Siena M. Duarte
Siena M.
Duarte
Esther L. Yuh
Esther L.
Yuh
Pratik Mukherjee
Pratik
Mukherjee
Sureyya S. Dikmen
Sureyya S.
Dikmen
Thomas W. McAllister
Thomas W.
McAllister
Ramon Diaz-Arrastia
Ramon
Diaz-Arrastia
Alex B. Valadka
Alex B.
Valadka
Wayne A. Gordon
Wayne A.
Gordon
David O. Okonkwo
David O.
Okonkwo
Geoffrey T. Manley
Geoffrey T.
Manley
Temporal profile of care following mild traumatic brain injury: predictors of hospital admission, follow-up referral and six-month outcome
Taylor & Francis Group
2018
Clinical evaluation
follow-up care
outcome assessment
rehabilitation
traumatic brain injury
2018-09-10 16:36:47
Journal contribution
https://tandf.figshare.com/articles/journal_contribution/Temporal_profile_of_care_following_mild_traumatic_brain_injury_predictors_of_hospital_admission_follow-up_referral_and_six-month_outcome/5627071
<p><i>Objective</i>: To investigate the clinical management and medical follow-up of patients with mild traumatic brain injury (mTBI) presenting to emergency departments (EDs). <i>Methods</i>: Overall, 168 adult patients with mTBI from the prospective, multicentre Transforming Research and Clinical Knowledge in TBI (TRACK-TBI) Pilot study with Glasgow Coma Scale (GCS) 13–15, no polytrauma and alive at six months were included. Predictors for hospital admission, three-month follow-up referral and six-month functional disability (Glasgow Outcome Scale-Extended (GOSE) ≤ 6) were analysed using multivariable regression. <i>Results</i>: Overall, 48% were admitted to hospital, 22% received three-month referral and 27% reported six-month functional disability. Intracranial pathology on ED head computed tomography (multivariable odds ratio (OR) = 81.08, 95% confidence interval (CI) [10.28–639.36]) and amnesia (>30-minutes: OR = 5.27 [1.75–15.87]; unknown duration: OR = 4.43 [1.26–15.62]) predicted hospital admission. Older age (per-year OR = 1.03 [1.01–1.05]) predicted three-month referral, while part-time/unemployment predicted lack of referral (OR = 0.17 [0.06–0.50]). GCS < 15 (OR = 2.46 [1.05–5.78]) and prior history of seizures (OR = 3.62 [1.21–10.89]) predicted six-month functional disability, while increased education (per-year OR = 0.86 [0.76–0.97]) was protective. <i>Conclusions</i>: Clinical factors modulate triage to admission, while demographic/socioeconomic elements modulate follow-up care acquisition; six-month functional disability associates with both clinical and demographic/socioeconomic variables. Improving triage to acute and outpatient care requires further investigation to optimize resource allocation and outcome after mTBI.</p> <p><b>ClinicalTrials.gov registration:</b> NCT01565551</p>