New angular oxazole-fused coumarin derivatives: synthesis and biological activities Yan Wei Shi-qiang Li Shuang-hong Hao 10.6084/m9.figshare.5619595.v1 https://tandf.figshare.com/articles/journal_contribution/New_angular_oxazole-fused_coumarin_derivatives_synthesis_and_biological_activities/5619595 <p>Twelve angular oxazole-fused coumarin derivatives were designed, synthesised and characterised by <sup>1</sup>H NMR, <sup>13</sup>C NMR and HRMS. The structure of compound <b>4a</b> was further confirmed by X-ray single-crystal diffraction. The bioassay experiment results indicated that compounds <b>4f</b> and <b>4l</b> have high antifungal activity on the mycelium growth of 4 plant disease fungi. Especially, compound <b>4l</b> has a stronger antifungal activity compare to the commercial fungicide, Carbendazim. The herbicidal activity experiment showed that <b>4a</b> and <b>4b</b> can significantly inhibit the taproot and caulis development of <i>Chenopodium album</i> seedling and have better activities than the commercial herbicide, Acetochlor.</p> 2017-11-21 02:53:15 Angular oxazole-fused coumarin synthesis antifungal activity herbicidal activity