Zhang, Song-Lin Wan, Hai-Xing Bie, Wen-Feng <i>syn</i>-Fluoro- and -Oxy-trifluoromethylation of Arylacetylenes One-step concurrent fluoro-trifluoromethylation across the triple bond of arylacetylenes in a <i>syn</i> mode is enabled by the collaboration of (phen)­Cu<sup>III</sup>(CF<sub>3</sub>)<sub>3</sub> and CsF that produces chemo-, regio-, and stereoselectively (Z)-α-fluoro-β-CF<sub>3</sub> styrenes. This method can be extended to achieve <i>syn</i>-oxy-trifluoromethylation and <i>syn</i>-aryl-trifluoromethylation of alkynes using phenoxides, alkoxides, or phenylboronic acid in place of CsF. It opens up new opportunities for preparing various functionalized trifluoromethylated <i>Z</i>-alkenes and demonstrates the potential of Cu­(III)–CF<sub>3</sub> complexes in organic synthesis. CsF;III;Arylacetylenes One-step;syn mode;phenylboronic acid;functionalized trifluoromethylated Z;CF 3 2017-11-18
    https://acs.figshare.com/articles/journal_contribution/_i_syn_i_-Fluoro-_and_-Oxy-trifluoromethylation_of_Arylacetylenes/5615443
10.1021/acs.orglett.7b03229.s001