%0 Journal Article %A Subhashini, N. J. P. %A Bhadraiah, B. %A Janaki, P. %A Sridhar, Gattu %D 2018 %T Total synthesis of patulolide A through ring closing metathesis %U https://tandf.figshare.com/articles/journal_contribution/Total_synthesis_of_Patulolide_A_i_via_i_ring_closing_metathesis/5612986 %R 10.6084/m9.figshare.5612986.v2 %2 https://ndownloader.figshare.com/files/9770083 %K 1,3-Dithiane %K AD-mix %K patulolide A %K ring closing metathesis %X

A simple and efficient total synthesis of patulolide A from readily available 7-octen-1-ol is reported by asymmetric synthetic approach. The key reactions involved are asymmetric dihydroxylation using AD-mix-β and Grubbs’ ring-closing metathesis reaction for the synthesis macrocyclic ring system.

%I Taylor & Francis