%0 Figure %A Schmidt, Katja %A Butt, Julia %A Mauter, Petra %A Vogel, Klaus %A Erles-Kemna, Andrea %A Pawlita, Michael %A Nicklas, Werner %D 2017 %T Schematic presentation of capsid processing as basis for the selection of amino acid sequences of MuAstV capsid proteins. %U https://plos.figshare.com/articles/figure/Schematic_presentation_of_capsid_processing_as_basis_for_the_selection_of_amino_acid_sequences_of_MuAstV_capsid_proteins_/5556814 %R 10.1371/journal.pone.0187174.g001 %2 https://ndownloader.figshare.com/files/9643072 %K laboratory mice Laboratory mice %K laboratory animal science %K 400 sera %K mouse strain %K MuAstV proteins %K Assay sensitivity %K assay %K murine astrovirus infections %K MuAstV status %K rodent health monitoring %K DKFZ %K RT-PCR results %K murine astroviruses %K high-throughput capability %K animal experiments %K laboratory mouse populations %K test 5529 serum samples %K laboratory mice %K health monitoring %K German Cancer Research Center %K MuAstV multiplex %K 2017. High sero-prevalence rates %K 661 mice %K 312 mice %K VP %K 15 countries %K 58 research institutes %X

The recombinant capsid proteins were used as antigens in multiplex MuAstV serology. VP70 long, VP34 and VP27 sequence fragments are based on processing data of human astrovirus capsid protein according to UniProt ID O12792 [24]. Cleavage sites are indicated by black arrowheads. VP70 short fragment is based on the predicted caspase cleavage site at aa position 554 as suggested by Expasy Peptide Cutter (white arrowhead). The figure was adapted from Krishna et al. [22] and modified by the authors.

%I PLOS ONE