10.1371/journal.pone.0185980.g007 Basetti Madhu Basetti Madhu Alexandra Jauhiainen Alexandra Jauhiainen Sean McGuire Sean McGuire John R. Griffiths John R. Griffiths Metabolic interactions between brain tumour cells and host cells. Public Library of Science 2017 brain tumour metabolism HR-MAS 1 H NMR spectra Methods glycolytic tumour cells Additional metabolite exchanges 75 meningiomas alanine 378 HRMAS 1 H NMR spectra pre-necrotic tumour tissue choline turnover lipid signals glutamine tumour types tumours co-opt metabolite-metabolite correlation analysis tCho tCr pool Warburg effect phosphocreatine-driven glutamate uptake 37 oligodendrogliomas host cells catabolic metabolites 101 astrocytomas mechanism cytosolic lipid droplets pairwise metabolite-metabolite correlation analysis eTumour database 33 metastases MMCA lactate 2017-10-25 17:29:23 Figure https://plos.figshare.com/articles/figure/Metabolic_interactions_between_brain_tumour_cells_and_host_cells_/5538550 <p>The lactate from tumour cell is transported to glial cells, where it is used a fuel to produce ATP. ATP and PCr are connected via the creatine-kinase reaction. PCr, phosphocreatine; Cr, creatine; TCA, tricarboxylic acid cycle.</p>