TY - DATA T1 - nSides: An interactive drug--side effect gateway PY - 2017/10/24 AU - Rami Vanguri AU - Joseph Romano AU - Tal Lorberbaum AU - Choonhan Youn AU - Victor Nwankwo AU - Nicholas Tatonetti UR - https://figshare.com/articles/dataset/nSides_An_interactive_drug--side_effect_gateway/5483698 DO - 10.6084/m9.figshare.5483698.v2 L4 - https://ndownloader.figshare.com/files/9485029 L4 - https://ndownloader.figshare.com/files/9579598 KW - Science Gateways KW - Science Gateways Community Institute KW - Gateways 2017 KW - drug activity KW - side effects KW - Clinical Pharmacology and Therapeutics N2 - Adverse drug events are a leading cause of morbidity and mortality around the world. Regulatory agencies, such as the Food and Drug Administration (FDA), maintain large collections of adverse event reports. These spontaneous reporting systems provide an opportunity to retrospectively study drug effects from patient population data. To make our results more accessible, we present a gateway to a new database of drug interactions (nSides) developed using the FDA Adverse Event Reporting System. Side effects for a variety of drugs and drug interactions are presented. Additionally, for high order drug combinations, with the support of the Science Gateway Community Institute's Extended Developer Support, we develop a novel system to request new models to be generated using the Open Science Grid on-demand. ER -