Ren, Anni Lang, Bo Lin, Jialun Lu, Ping Wang, Yanguang 4‑Diazoisochroman-3-imines: A Class of Metal Carbene Precursors for the Synthesis of Isochromene Derivatives 4-Diazoisochroman-3-imines were investigated for their synthetic applications as a new class of metal carbene precursors. Under the catalysis from a Rh­(II) complex, this class of α-diazo imidates reacted with alkenes and conjugated dienes through a formal [2 + 1] (i.e., cyclopropanation) or [4 + 3] cycloaddition to furnish spiro­[cyclopropane-1,4′-isochroman]-3′-imines and tetrahydroisochromeno­[3,4-<i>b</i>] azepines, respectively. When Rh­(II)/AgOTf was used as cocatalyst, the formal [3 + 2] cycloaddition of 4-diazoisochroman-3-imines with terminal alkynes took place, leading to the synthesis of 2-aryl-3,5-dihydroisochromeno­[3,4-<i>b</i>]­pyrroles. Isochromene Derivatives 4- Diazoisochroman -3-imines;terminal alkynes;metal carbene precursors;Rh;cycloaddition;α- diazo imidates;4- diazoisochroman -3-imines;Metal Carbene Precursors 2017-09-27
    https://acs.figshare.com/articles/dataset/4_Diazoisochroman-3-imines_A_Class_of_Metal_Carbene_Precursors_for_the_Synthesis_of_Isochromene_Derivatives/5479570
10.1021/acs.joc.7b01860.s002