TY - DATA T1 - Additional file 1: Figure S1. of S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis PY - 2017/09/29 AU - Niels Cremers AU - Martijn H. J. van den Bosch AU - Stephanie van Dalen AU - Irene Di Ceglie AU - Giuliana Ascone AU - Fons van de Loo AU - Marije Koenders AU - Peter van der Kraan AU - Annet Sloetjes AU - Thomas Vogl AU - Johannes Roth AU - Edwin Geven AU - Arjen Blom AU - Peter van Lent UR - https://springernature.figshare.com/articles/presentation/Additional_file_1_Figure_S1_of_S100A8_A9_increases_the_mobilization_of_pro-inflammatory_Ly6Chigh_monocytes_to_the_synovium_during_experimental_osteoarthritis/5462896 DO - 10.6084/m9.figshare.c.3894754_D1.v1 L4 - https://ndownloader.figshare.com/files/9446824 KW - S100 KW - Mobilization KW - Ly6C high/low monocytes KW - Systemic effects KW - Collagenase-induced osteoarthritis N2 - S100A8/A9 protein levels are systemically elevated in the serum during early CiOA. Systemic levels of S100A8/A9 protein in serum of WT mice are increased early during CiOA compared to saline-injected control mice, measured using ELISA. Data represent mean ± SD of five individual mice per group per time point. *Significantly different from saline-injected control (*p < 0.05, **p < 0.01, ***p < 0.001). Figure S2. Expression of adhesion molecules is lower in the BM of WT mice, compared to S100a9-/- mice, at CiOA day 7. mRNA expression of several adhesion molecules is lower in the BM of S100a9-/- mice compared to WT mice at CiOA day 7. Data represent mean ± SD of five individual mice. *Significantly different from saline-injected control (*p < 0.05, **p < 0.01, ***p < 0.001). (PPT 142 kb) ER -