%0 Online Multimedia %A Cremers, Niels %A van den Bosch, Martijn H. J. %A van Dalen, Stephanie %A Di Ceglie, Irene %A Ascone, Giuliana %A van de Loo, Fons %A Koenders, Marije %A van der Kraan, Peter %A Sloetjes, Annet %A Vogl, Thomas %A Roth, Johannes %A Geven, Edwin %A Blom, Arjen %A van Lent, Peter %D 2017 %T Additional file 1: Figure S1. of S100A8/A9 increases the mobilization of pro-inflammatory Ly6Chigh monocytes to the synovium during experimental osteoarthritis %U https://springernature.figshare.com/articles/presentation/Additional_file_1_Figure_S1_of_S100A8_A9_increases_the_mobilization_of_pro-inflammatory_Ly6Chigh_monocytes_to_the_synovium_during_experimental_osteoarthritis/5462896 %R 10.6084/m9.figshare.c.3894754_D1.v1 %2 https://ndownloader.figshare.com/files/9446824 %K S100 %K Mobilization %K Ly6C high/low monocytes %K Systemic effects %K Collagenase-induced osteoarthritis %X S100A8/A9 protein levels are systemically elevated in the serum during early CiOA. Systemic levels of S100A8/A9 protein in serum of WT mice are increased early during CiOA compared to saline-injected control mice, measured using ELISA. Data represent mean ± SD of five individual mice per group per time point. *Significantly different from saline-injected control (*p < 0.05, **p < 0.01, ***p < 0.001). Figure S2. Expression of adhesion molecules is lower in the BM of WT mice, compared to S100a9-/- mice, at CiOA day 7. mRNA expression of several adhesion molecules is lower in the BM of S100a9-/- mice compared to WT mice at CiOA day 7. Data represent mean ± SD of five individual mice. *Significantly different from saline-injected control (*p < 0.05, **p < 0.01, ***p < 0.001). (PPT 142 kb) %I figshare