Niu, Xiaomei Nouraie, Mehdi Campbell, Andrew Rana, Sohail P. Minniti, Caterina Sable, Craig Darbari, Deepika Dham, Niti Scott Reading, N. T. Prchal, Josef J. Kato, Gregory Gladwin, Mark T. L. Castro, Oswaldo R. Gordeuk, Victor Pathway analysis of tricuspid regurgitation velocity in sickle cell disease patients. <p>The numbers shown are standardized betas. Each of the arrows depicts a significant relationship (P<0.05). According to this analysis, higher hemolytic component was a direct predictor of increasing tricuspid regurgitation velocity and it also was associated with lower hemoglobin concentration and higher interleukin-6 concentration. Lower hemoglobin concentration was not a direct predictor of higher regurgitation velocity, but it was associated with higher VEGF concentration. Higher interleukin-6 concentration was a direct predictor of increasing tricuspid regurgitation velocity and it also was associated with higher VEGF and PDGF-BB concentrations. Higher PDGF-BB concentration was a direct predictor of increasing regurgitation velocity while higher VEGF concentration was a direct predictor of lower regurgitation velocity.</p> tricuspid;regurgitation;velocity;sickle 2013-02-21
    https://plos.figshare.com/articles/figure/_Pathway_analysis_of_tricuspid_regurgitation_velocity_in_sickle_cell_disease_patients_/545452
10.1371/journal.pone.0007956.g003