The effects of improved efficacy associated with treating late-stage disease and the effects of over-diagnosis for the years 1982–2013. Stephen Gilmore 10.1371/journal.pone.0182349.g005 https://plos.figshare.com/articles/figure/The_effects_of_improved_efficacy_associated_with_treating_late-stage_disease_and_the_effects_of_over-diagnosis_for_the_years_1982_2013_/5438104 <p><b>(a)</b> Average mortality reductions per year per 100,000 persons as a function of <b><i>q</i></b> for all <b><i>p</i></b> where <b><i>D</i></b><i>(0)</i> = 0.01 and <b>(b) <i>D</i></b><i>(0)</i> = 0.05. Note the robustness of results with respect to both <b><i>p</i></b> and <b><i>D</i></b><i>(t)</i> (all five plots for different values of <b><i>p</i></b> are closely superimposed). <b>(c)</b> Excess diagnoses per 100,000 persons as a function of maximal over-diagnosis proportion for all <b><i>p</i></b> where <b><i>D</i></b><i>(0)</i> = 0.01 and <b>(d) <i>D</i></b><i>(0)</i> = 0.05.</p> 2017-09-25 17:31:55 New Zealand share sun exposure practices mass media campaigns melanoma surveillance constraint-based surveillance outcomes mortality late-stage disease survival incidence prevention