TY - DATA T1 - Additional file 1: Figure S1. of Preventive effects of the novel antimicrobial peptide Nal-P-113 in a rat Periodontitis model by limiting the growth of Porphyromonas gingivalis and modulating IL-1β and TNF-α production PY - 2017/08/29 AU - Hong-yan Wang AU - Li Lin AU - Wei Fu AU - Hui-Yuan Yu AU - Ning Yu AU - Li-si Tan AU - Jya-wei Cheng AU - Ya-ping Pan UR - https://springernature.figshare.com/articles/figure/Additional_file_1_Figure_S1_of_Preventive_effects_of_the_novel_antimicrobial_peptide_Nal-P-113_in_a_rat_Periodontitis_model_by_limiting_the_growth_of_Porphyromonas_gingivalis_and_modulating_IL-1_and_TNF-_production/5357284 DO - 10.6084/m9.figshare.c.3866608_D1.v1 L4 - https://ndownloader.figshare.com/files/9208225 KW - Antimicrobial peptide KW - Animal model KW - Periodontitis KW - Alveolar bone loss KW - Inflammatory response KW - Porphyromonas gingivalis N2 - (A) IL-1β levels of immortalized human gingival epithelial cells, human periodontal ligament stem cells and macrophages after co-cultured with Nal-P-113 for 2 h. Nal-P-113 (25 μg/mL or 400 μg/mL) did not change the levels of IL-1β expression in immortalized human gingival epithelial cells, human periodontal ligament stem cells or macrophages detected by enzyme-linked immunosorbent assay (P > 0.05). (B) TNF-α levels of immortalized human gingival epithelial cells, human periodontal ligament stem cells and macrophages after co-cultured with Nal-P-113 for 2 h. Nal-P-113 (25 μg/mL or 400 μg/mL) increased TNF-α levels in periodontal ligament cells (P < 0.05), but not in gingival epithelial cells or macrophages (P > 0.05). (JPEG 453 kb) ER -