Meyers, Robin CERES - Meyers, Bryan, et al. Nature Genetics. 2017. Datasets used in CERES publication.<div>Meyers, Bryan, et al. Computational correction of copy-number effect improves specificity of CRISPR-Cas9 essentiality screens in cancer cells. Nature Genetics. 2017.<br><div><br></div></div><div>External data:</div><div><br></div><div>CCLE_copynumber_2013-12-03.seg.txt<br></div><div>CCLE copy number data downloaded from https://data.broadinstitute.org/ccle_legacy_data/dna_copy_number/CCLE_copynumber_2013-12-03.seg.txt</div><div><br></div><div>CCLE_RNAseq_081117.rpkm.gct</div><div>CCLE gene expression data downloaded from https://data.broadinstitute.org/ccle/CCLE_RNAseq_081117.rpkm.gct<br></div><div><br></div><div>ccle2maf_081117.txt</div><div>CCLE mutation data downloaded from https://data.broadinstitute.org/ccle/ccle2maf_081117.txt<br></div><div><br></div><div>Achilles_v2.20.2_GeneSolutions.gct<br></div><div>RNAi DEMETER gene dependencies downloaded from https://portals.broadinstitute.org/achilles/datasets/12/download/Achilles_v2.20.2_GeneSolutions.gct</div><div><br></div><div>CCDS.current.txt</div><div>CCDS gene annotations downloaded from ftp://ftp.ncbi.nlm.nih.gov/pub/CCDS/archive/15/CCDS.current.txt</div><div><br></div><div>c2.all.v6.0.symbols.gmt </div><div>MSigDB genesets downloaded from http://software.broadinstitute.org/gsea/msigdb/download_file.jsp?filePath=/resources/msigdb/6.0/c2.all.v6.0.symbols.gmt<br></div><div><br></div><div>avana_rs2.txt and gecko_rs2.txt</div><div>Doench-Root scores for sgRNAs provided by authors of Doench, et al. Nat. Biotechnol. 2016.</div> <div> <div> <div> <p><br> </p><p>wang_pool_normalized.counts.txt</p><p>Downloaded from supplement of Wang, et al. Cell. 2017.</p> </div> </div> </div><div><br></div> CERES;CRISPR-Cas9;Copy-number effect;Essentiality screens;Cancer cell lines;Computational models;Cancer genomics;Cancer;Computational Biology;Genomics;Bioinformatics;Bioinformatics Software;Cancer Genetics 2017-10-30
    https://figshare.com/articles/dataset/CERES_-_Meyers_Bryan_et_al_Nature_Genetics_2017_/5319388
10.6084/m9.figshare.5319388.v2