Diastereoselective Synthesis of Diquinanes and Triquinanes Bearing Vicinal Quaternary Carbon Stereocenters from Acyclic Allene-based Precursors via a Cascade Reaction Shuang Li Pengpeng Zhang Yuanhe Li Shumin Lu Jianxian Gong Zhen Yang 10.1021/acs.orglett.7b01733.s001 https://acs.figshare.com/articles/journal_contribution/Diastereoselective_Synthesis_of_Diquinanes_and_Triquinanes_Bearing_Vicinal_Quaternary_Carbon_Stereocenters_from_Acyclic_Allene-based_Precursors_via_a_Cascade_Reaction/5305360 A cascade benzenethiol-mediated intramolecular [3 + 2] cycloaddition reaction between an allene and an α,β-unsaturated aldehyde or ester is developed for the diastereoselective synthesis of [3.3.0] bicyclic system bearing two quaternary atoms at their bridgehead positions. Notably, these structurally complex systems can be found in a wide range of natural products. 2017-08-11 18:33:52 bicyclic Triquinanes Bearing Vicinal Quaternary Carbon Stereocenters Cascade Reaction intramolecular Diastereoselective Synthesis cycloaddition bridgehead positions aldehyde allene ester Diquinane benzenethiol-mediated Acyclic Allene-based Precursors diastereoselective synthesis quaternary atoms cascade