Vitale, Serena Strisciuglio, Caterina Pisapia, Laura Miele, Erasmo Barba, Pasquale Vitale, Alessandra Cenni, Sabrina Bassi, Virginia Maglio, Mariantonia Del Pozzo, Giovanna Troncone, Riccardo Staiano, Annamaria Gianfrani, Carmen Expansion of enterocytes expressing IL-15 in intestinal mucosa of paediatric patients with IBD. <p>Enterocytes were identified as EpCam positive cells. (<b>A</b>) The percentage of EpCam positive cells, and (<b>B</b>) IL-15 and EpCam double positive cells were evaluated in freshly isolated intestinal cells, at basal condition without <i>in vitro</i> mitogen stimulation. Each point represents the percentage of positive cells from one single subject.(<b>C</b>) Flowcytometry dot plots of IL-15 and EpCam stained cells are reported from one representative subject of each group (CD, UC, HC). Horizontal bars are the median values. The Mann-Whitney U test was applied to evaluate statistical significant differences.</p> mucosa;IBD patients;organ culture supernatants;HC;IFN;enzyme-linked immunosorbent assay;INF;UC;IL -15;ELISA;Cytokine production profile;cell culture supernatants;IL -15 blockage;enterocyte;bowel disease;cytokine;TNF;neutralizing anti-IL -15;CD 11c cells 2017-08-10
    https://plos.figshare.com/articles/figure/Expansion_of_enterocytes_expressing_IL-15_in_intestinal_mucosa_of_paediatric_patients_with_IBD_/5299780
10.1371/journal.pone.0182313.g003