Schüler, Svenja
Kieser, Meinhard
Rauch, Geraldine
Additional file 4 of Choice of futility boundaries for group sequential designs with two endpoints
Probability of stopping for futility and overall power for Approach 3. Plot of probability of stopping for futility (left figure) and overall power (right figure) for Approach 3 using the futility β γ-boundaries α f CE = 0.69 $ \alpha_{f}^{CE}=0.69$ and α f MC = 0.65 $ \alpha_{f}^{MC}=0.65$ for composite endpoint and main component, respectively. (JPG 202 kb)
Group sequential design;Stopping for futility;Two endpoints;Intersection-union test
2017-08-08
https://springernature.figshare.com/articles/Additional_file_4_of_Choice_of_futility_boundaries_for_group_sequential_designs_with_two_endpoints/5287804

10.6084/m9.figshare.c.3846742_D4.v1