Additional file 4 of Choice of futility boundaries for group sequential designs with two endpoints
SchülerSvenja
KieserMeinhard
RauchGeraldine
2017
Probability of stopping for futility and overall power for Approach 3. Plot of probability of stopping for futility (left figure) and overall power (right figure) for Approach 3 using the futility β γ-boundaries α f CE = 0.69 $ \alpha_{f}^{CE}=0.69$ and α f MC = 0.65 $ \alpha_{f}^{MC}=0.65$ for composite endpoint and main component, respectively. (JPG 202 kb)