TY - DATA T1 - Erratum: 14 Years of Polish Experience in Non-Invasive Prenatal Blood Group Diagnosis PY - 2017/07/25 AU - Orzińska A. AU - Guz K. AU - Dębska M. AU - Uhrynowska M. AU - Celewicz Z. AU - Wielgoś M. AU - Brojer E. UR - https://karger.figshare.com/articles/dataset/Erratum_14_Years_of_Polish_Experience_in_Non-Invasive_Prenatal_Blood_Group_Diagnosis/5241859 DO - 10.6084/m9.figshare.5241859.v1 L4 - https://ndownloader.figshare.com/files/8956582 KW - Non-invasive prenatal diagnostics KW - Alloimmunization KW - Real-time PCR N2 - Background: Blood cell antigens may cause maternal alloimmunization leading to fetal/newborn disorders. Non-invasive prenatal diagnostics (NIPD) of the blood group permits the determination of feto-maternal incompatibility. Aim: To evaluate 14 years of blood group NIPD at the Institute of Hematology and Transfusion Medicine (IHTM) in Warsaw. Methods: Plasma DNA from 536 RhD-negative, 24 Rhc-negative, 26 RhE-negative, 43 K-negative, and 42 HPA-1a-negative pregnant women was examined by real-time PCR to detect RHD, RHCE*c, RHCE*E, RHCE*C,KEL*01 and HPA*1A, respectively. We tested for CCR5, SRY or bi-allelic polymorphisms and quantified the total or fetal DNA. Results: The results of fetal antigen status prediction by NIPD in all but one case (false-positive result of KEL*01) were correct taking neonate serology as a reference. It was confirmed that all negative results of NIPD contained fetal DNA except for four cases where there was no difference between the parents' polymorphisms. Conclusions: A fetal genotype compatible with the mother was determined in 25% of all pregnancies tested at the IHTM for the fetal blood group. These cases were not at risk of disease, so it was possible to avoid invasive procedures. ER -