10.6084/m9.figshare.5212558 Quy Hung Trieu Quy Hung Trieu Huong Doan Thi Mai Huong Doan Thi Mai Marc Litaudon Marc Litaudon Dao Phi Thi Dao Phi Thi Tuan Anh Tran Tuan Anh Tran Van Hung Nguyen Van Hung Nguyen Van Minh Chau Van Minh Chau Van Cuong Pham Van Cuong Pham Two new linear acetogenins from the fruits of <i>Goniothalamus gracilipes</i> Taylor & Francis Group 2017 Annonaceae Goniothalamus gracilipes Gracilipin A methyl-saccopetrin A cytotoxic activity 2017-07-17 06:21:53 Journal contribution https://tandf.figshare.com/articles/journal_contribution/Two_new_linear_acetogenins_from_the_fruits_of_i_Goniothalamus_gracilipes_i_/5212558 <p>Two new linear acetogenins, gracilipin A (<b>1</b>) and methylsaccopetrin A (<b>2</b>) along with seven known compounds, saccopetrin A (<b>3</b>), 7,3′,4′-trimethylquercetin (<b>4</b>), rhamnazin (<b>5</b>), casticin (<b>6</b>), isokanugin (<b>7</b>), melisimplexin (<b>8</b>) and 5-hydroxy-3,7-dimethoxy-3′,4′-methylenedioxyflavone (<b>9</b>) were isolated from the fruits of <i>Goniothalamus gracilipes</i> Bân. Their structures were established by spectral analysis, such as mass spectrometry, 1D-NMR, 2D-NMR and circular dichroism (CD). Compounds <b>1</b> and <b>3</b> showed cytotoxic activity against KB cell line with IC<sub>50</sub> values of 14.6 and 15.3 μM, respectively.</p>