Changes in the frequency of CD16<sup>+</sup>, CD56<sup>+</sup> and CD16<sup>-</sup>CD56<sup>-</sup> NK cells expressing KIR3DL01 and KIR3DL05.
Moritz Ries
Matthew R. Reynolds
Ksenia Bashkueva
Kristin Crosno
Saverio Capuano III
Trent M. Prall
Roger Wiseman
David H. O’Connor
Eva G. Rakasz
Hajime Uno
Jeffrey D. Lifson
David T. Evans
10.1371/journal.ppat.1006506.g002
https://plos.figshare.com/articles/figure/Changes_in_the_frequency_of_CD16_sup_sup_CD56_sup_sup_and_CD16_sup_-_sup_CD56_sup_-_sup_NK_cells_expressing_KIR3DL01_and_KIR3DL05_/5211223
<p>The percentages of CD16<sup>+</sup>, CD56<sup>+</sup> and CD16<sup>-</sup>CD56<sup>-</sup> NK cells that are KIR3DL01<sup>+</sup> (A), KIR3DL05<sup>+</sup> (B) or KIR3DL01<sup>-</sup>05<sup>-</sup> (C) were monitored in peripheral blood. The mean and standard error (error bars) are shown for each subset. Significance values were calculated using a mixed effects model by comparing the results from acute (weeks 1–4) and chronic (weeks 6–24) infection to pre-infection (week 0) and are indicated with asterisks color-coded according to the corresponding NK cell population (p<0.05*, p<0.01**, p< 0.005*** & p<0.001****).</p>
2017-07-14 17:51:38
CD 107a
TNF α upregulation
HLA-DR
NK cell activation
NK cell responses
NK cells
Mamu-Bw 4 molecules
interactions influence NK cell responses
SIV infection
KIR 3DL
CD 16
KIR 3DL upregulation
MHC class I-defined rhesus macaques Natural killer cells
CD 56
polymorphic killer-cell immunoglobulin-like receptors
gut-associated lymphoid tissues
MHC class