Changes in the frequency of CD16<sup>+</sup>, CD56<sup>+</sup> and CD16<sup>-</sup>CD56<sup>-</sup> NK cells expressing KIR3DL01 and KIR3DL05. Moritz Ries Matthew R. Reynolds Ksenia Bashkueva Kristin Crosno Saverio Capuano III Trent M. Prall Roger Wiseman David H. O’Connor Eva G. Rakasz Hajime Uno Jeffrey D. Lifson David T. Evans 10.1371/journal.ppat.1006506.g002 https://plos.figshare.com/articles/figure/Changes_in_the_frequency_of_CD16_sup_sup_CD56_sup_sup_and_CD16_sup_-_sup_CD56_sup_-_sup_NK_cells_expressing_KIR3DL01_and_KIR3DL05_/5211223 <p>The percentages of CD16<sup>+</sup>, CD56<sup>+</sup> and CD16<sup>-</sup>CD56<sup>-</sup> NK cells that are KIR3DL01<sup>+</sup> (A), KIR3DL05<sup>+</sup> (B) or KIR3DL01<sup>-</sup>05<sup>-</sup> (C) were monitored in peripheral blood. The mean and standard error (error bars) are shown for each subset. Significance values were calculated using a mixed effects model by comparing the results from acute (weeks 1–4) and chronic (weeks 6–24) infection to pre-infection (week 0) and are indicated with asterisks color-coded according to the corresponding NK cell population (p<0.05*, p<0.01**, p< 0.005*** & p<0.001****).</p> 2017-07-14 17:51:38 CD 107a TNF α upregulation HLA-DR NK cell activation NK cell responses NK cells Mamu-Bw 4 molecules interactions influence NK cell responses SIV infection KIR 3DL CD 16 KIR 3DL upregulation MHC class I-defined rhesus macaques Natural killer cells CD 56 polymorphic killer-cell immunoglobulin-like receptors gut-associated lymphoid tissues MHC class