TY - DATA T1 - A new furofuran lignan from Piper terminaliflorum Tseng PY - 2017/07/10 AU - Tie Liu AU - Qian Liang AU - Xin-Min Zhang AU - Shen-Yang Huang AU - Wen-Hui Xu UR - https://tandf.figshare.com/articles/journal_contribution/A_new_furofuran_lignan_from_i_Piper_terminaliflorum_i_Tseng/5189125 DO - 10.6084/m9.figshare.5189125 L4 - https://ndownloader.figshare.com/files/8851243 KW - Piper terminaliflorum Tseng KW - furofuran lignan KW - amide alkaloid KW - cytotoxic activities N2 - The chemical investigation of whole plants Piper terminaliflorum Tseng led to the isolation of one new furofuran lignan, 7-methoxyasarinin (1), along with three known amide alkaloids (2–4) as N-3,5-dimethoxy-4-hydroxycinnamoylpyrrole (2), dihydropipercide (3) and 1-[(2E,4E,9E)-10-(3,4-Methylenedioxyphenyl)-2,4,9-undecatrienoyl]pyrrolidine (4). Their structures were elucidated by extensive spectroscopic analyses, including 1D, 2D NMR and HR-ESI-MS, and by comparison with the literature. Compounds (2–4) were isolated from Piper terminaliflorum Tseng for the first time. All isolated compounds (1–4) were evaluated for their cytotoxic activities against five human cancer cell lines (including A-549, SMMC-7721, HL-60, MCF-7 and SW-480). ER -