TY - DATA T1 - Pittsburgh Mind-Body Center Study (PMBC) PY - 2017/06/28 AU - Sheldon Cohen AU - Cuneyt M. Alper AU - Andrew S. Baum AU - Margaret Clark AU - William Doyle AU - Bruce S. Rabin AU - John J. Treanor AU - Ronald B. Turner UR - https://kilthub.cmu.edu/articles/dataset/Pittsburgh_Mind-Body_Center_Study_PMBC_/5142277 DO - 10.1184/RDL/1502011 L4 - https://ndownloader.figshare.com/files/8749294 L4 - https://ndownloader.figshare.com/files/8749297 L4 - https://ndownloader.figshare.com/files/8749300 L4 - https://ndownloader.figshare.com/files/8749303 L4 - https://ndownloader.figshare.com/files/8749306 L4 - https://ndownloader.figshare.com/files/8749309 L4 - https://ndownloader.figshare.com/files/8749312 L4 - https://ndownloader.figshare.com/files/8749315 L4 - https://ndownloader.figshare.com/files/8749318 L4 - https://ndownloader.figshare.com/files/8749321 L4 - https://ndownloader.figshare.com/files/8749324 KW - Psychoneuroimmunology KW - Common Cold KW - Health Behavior KW - disease susceptibility KW - Marital Relationship KW - Cytokine analysis KW - viral antibodies KW - DataONE N2 - The Pittsburgh Mind-Body Center (PMBC) Study was a prospective viral challenge study conducted from 2000-2004 among healthy volunteers ages 21-55 (mean age 37.3; SD 8.8). This study included detailed daily interviews with participants over 14 consecutive days to assess social interactions (number of interactions, with whom they were interacting, etc.), mood, and health behaviors. PMBC also included in-depth measurement of various aspects of marital relationships, including relationship satisfaction, spousal social support, marital commitment, and spousal self-disclosure. In addition (as part of the broader Mind-Body Center Project) numerous other psychological and behavioral variables were assessed including personal attributes, social factors, socioeconomic status, and health practices. Biological assessments before viral challenge included epinephrine, norepinephrine, cortisol, and stimulated cytokine production. Post-challenge measures, in addition to standard virology, included local (nasal secretions) cytokines (interleukin [IL]-1β, IL-6, IL-8, IL-10, IFN-α, and TNF-α).PMBC study documentation including details of measures used to collect the data and how variables were created can be obtained from the Common Cold Project website (www.cmu.edu/common-cold-project) ER -