Supplementary Material for: Self-Report Daily Life Activity as a Prognostic Marker of Idiopathic Pulmonary Fibrosis Leuchte H.H. Mernitz P. Baezner C. Baumgartner R.A. von Wulffen W. Neurohr C. Behr J. 10.6084/m9.figshare.5128900.v1 https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Self-Report_Daily_Life_Activity_as_a_Prognostic_Marker_of_Idiopathic_Pulmonary_Fibrosis/5128900 <b><i>Background:</i></b> Idiopathic pulmonary fibrosis (IPF) is a progressive disease, leading to substantial physical impairment. The distance walked in 6 min (6MWD) is a measure of exercise tolerance and is of prognostic relevance in IPF. While 6MWD is a punctual measurement which may not be representative, self-reported daily life activity may represent the patients' functional capacity more globally even in less severe affected patients. <b><i>Objectives:</i></b> We evaluated and characterized a simple classification system based on the patients' self-reported daily activity and analyzed if this would add significantly to the prognostic information of the 6MWD alone in IPF patients. <b><i>Methods:</i></b> Daily life activity was assessed in IPF (n = 156) patients with standardized questions and categorized in activity classes (AC I-IV), comprising the less severe impaired in AC I and II. The 6MWD was also assessed. <b><i>Results:</i></b> ACs were related to the lung functional impairment and inversely correlated to the 6MWD. Thirty-two patients were in AC I/II, 98 in AC III and 26 patients in AC IV. Thirty-seven (23.7%) patients died during a median follow-up of 14.9 months, comprising 1 patient in AC I/II. In addition, a 6MWD <470 m predicted mortality. Combining AC I/II and a 6MWD >470 m identified a subgroup of patients with favorable outcome. <b><i>Conclusions:</i></b> AC is a novel scoring system which can easily be obtained and correlates with lung functional and physical impairments as well as mortality. Moreover, AC adds prognostic information to the 6MWD. 2015-11-27 00:00:00 Idiopathic pulmonary fibrosis Six-minute walk test Dyspnea Health-related quality of life Idiopathic interstitial pneumonia