%0 Generic
%A H., Hsieh
%A S., McGrory
%A F., Leslie
%A K., Dawson
%A S., Ahmed
%A C.R., Butler
%A J.B., Rowe
%A E., Mioshi
%A J.R., Hodges
%D 2014
%T Supplementary Material for: The Mini-Addenbrooke's Cognitive Examination: A New Assessment Tool for Dementia
%U https://karger.figshare.com/articles/dataset/Supplementary_Material_for_The_Mini-Addenbrooke_s_Cognitive_Examination_A_New_Assessment_Tool_for_Dementia/5126944
%R 10.6084/m9.figshare.5126944.v1
%2 https://ndownloader.figshare.com/files/8714464
%K Cognitive screening test
%K Frontotemporal dementia
%K Alzheimer’s disease
%K Corticobasal degeneration
%X Background/Aims: We developed and validated the Mini-Addenbrooke's Cognitive Examination (M-ACE) in dementia patients. Comparisons were also made with the Mini Mental State Examination (MMSE). Method: The M-ACE was developed using Mokken scaling analysis in 117 dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n = 9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD, n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE. Results: The M-ACE consists of 5 items with a maximum score of 30. Two cut-offs were identified: (1) ≤25/30 has both high sensitivity and specificity, and (2) ≤21/30 is almost certainly a score to have come from a dementia patient regardless of the clinical setting. The M-ACE is more sensitive than the MMSE and is less likely to have ceiling effects. Conclusion: The M-ACE is a brief and sensitive cognitive screening tool for dementia. Two cut-offs (25 or 21) are recommended. © 2014 S. Karger AG, Basel
%I Karger Publishers