%0 Generic %A H., Hsieh %A S., McGrory %A F., Leslie %A K., Dawson %A S., Ahmed %A C.R., Butler %A J.B., Rowe %A E., Mioshi %A J.R., Hodges %D 2014 %T Supplementary Material for: The Mini-Addenbrooke's Cognitive Examination: A New Assessment Tool for Dementia %U https://karger.figshare.com/articles/dataset/Supplementary_Material_for_The_Mini-Addenbrooke_s_Cognitive_Examination_A_New_Assessment_Tool_for_Dementia/5126944 %R 10.6084/m9.figshare.5126944.v1 %2 https://ndownloader.figshare.com/files/8714464 %K Cognitive screening test %K Frontotemporal dementia %K Alzheimer’s disease %K Corticobasal degeneration %X Background/Aims: We developed and validated the Mini-Addenbrooke's Cognitive Examination (M-ACE) in dementia patients. Comparisons were also made with the Mini Mental State Examination (MMSE). Method: The M-ACE was developed using Mokken scaling analysis in 117 dementia patients [behavioural variant frontotemporal dementia (bvFTD), n = 25; primary progressive aphasia (PPA), n = 49; Alzheimer's disease (AD), n = 34; corticobasal syndrome (CBS), n = 9] and validated in an independent sample of 164 dementia patients (bvFTD, n = 23; PPA, n = 82; AD, n = 38; CBS, n = 21) and 78 controls, who also completed the MMSE. Results: The M-ACE consists of 5 items with a maximum score of 30. Two cut-offs were identified: (1) ≤25/30 has both high sensitivity and specificity, and (2) ≤21/30 is almost certainly a score to have come from a dementia patient regardless of the clinical setting. The M-ACE is more sensitive than the MMSE and is less likely to have ceiling effects. Conclusion: The M-ACE is a brief and sensitive cognitive screening tool for dementia. Two cut-offs (25 or 21) are recommended. © 2014 S. Karger AG, Basel %I Karger Publishers