10.1371/journal.pone.0179936.g004
Zheng Zhao
Zheng
Zhao
Lei Xie
Lei
Xie
Philip E. Bourne
Philip E.
Bourne
Two conserved interatomic interactions between MEK and the ligand.
Public Library of Science
2017
MEK type-III kinase inhibitors
type-III kinase inhibitors
helix-folding activation loop
Type-III kinase inhibitors
allosteric binding sites
type-III inhibitors
MEK-targeted type-III inhibitors
binding mode
kinome Protein kinases
allosteric kinase inhibitors
MEK type-III inhibitors
hallmark allosteric binding site
2017-06-19 17:42:42
Figure
https://plos.figshare.com/articles/figure/Two_conserved_interatomic_interactions_between_MEK_and_the_ligand_/5119534
<p>(a) Interatomic distances for every conformation from the MD trajectory; (b) The probability distribution of interatomic distances.</p>