%0 Figure %A Nishihara, Reiko %A Glass, Kimberly %A Mima, Kosuke %A Hamada, Tsuyoshi %A Nowak, Jonathan %A Qian, Zhi %A Kraft, Peter %A Giovannucci, Edward %A Fuchs, Charles %A Chan, Andrew %A Quackenbush, John %A Ogino, Shuji %A Onnela, Jukka-Pekka %D 2017 %T Additional file 1: Figure S1. of Biomarker correlation network in colorectal carcinoma by tumor anatomic location %U https://springernature.figshare.com/articles/figure/Additional_file_1_Figure_S1_of_Biomarker_correlation_network_in_colorectal_carcinoma_by_tumor_anatomic_location/5116996 %R 10.6084/m9.figshare.c.3805510_D1.v1 %2 https://ndownloader.figshare.com/files/8689612 %K biomarker network %K colorectal carcinoma %K MSI %K Bonferroni correction %K neoplastic epithelial cells %K correlation coefficient %K microsatellite instability %K line width %K TIFF 344 KB %K Biomarker correlation network %K significance level %K colorectal cancer %K TIL %K CDKN 2A %K IHC %K CDKN 2A CDKN 2A methylation level %K Spearman correlation %X The biomarker network in colorectal cancer. A node represents a molecular feature, and an edge specifies the Spearman correlation between two markers with a significance level of 3.5 × 10−5 (0.05/1431, based on the Bonferroni correction). The red line indicates a positive correlation, and the blue line indicates a negative correlation. The line width is proportional to a correlation coefficient. CDKN2A (IHC), protein expression of CDKN2A; CDKN2A, methylation level of CDKN2A; LINE-1, methylation level of long interspersed nucleotide element 1; MSI, microsatellite instability; TIL, lymphocytes on top of neoplastic epithelial cells. (TIFF 344 KB) %I figshare