%0 Figure %A Haase, Tobias %A Haase, Nadine %A Robert Kraehling, Jan %A Behrends, Soenke %D 2010 %T Proposed model of the heterodimeric sGC enzyme complex based on the results of FRET analysis and fusion of sGC subunits. %U https://plos.figshare.com/articles/figure/_Proposed_model_of_the_heterodimeric_sGC_enzyme_complex_based_on_the_results_of_FRET_analysis_and_fusion_of_sGC_subunits_/511416 %R 10.1371/journal.pone.0011617.g006 %2 https://ndownloader.figshare.com/files/840963 %K heterodimeric %K sgc %K enzyme %K fret %K fusion %X

The dimensions of the domains are given on the basis of the crystal structures of domain homologues (H-NOX, PDB ID 2O09 [9]; PAS, PDB ID 2P04 [13]; cat PDB ID 3ET6 [5]) and the structure of the coiled coil domain of the β1 subunit (PDB ID 3HLS [18]). Elongated model of the sGC (A). Model according to our results (B). Model of fluorescent-conjoined sGC (C). The β1 subunit is shown in red and the α subunit is shown in blue. cat - catalytic domain, CC - coiled coil region, PAS - Per-Arnt-Sim fold, HNOX - heme nitric oxide/oxygen binding domain.

%I PLOS ONE