10.1371/journal.pone.0012337.g003 Brendan P. Flynn Brendan P. Flynn Amit P. Bhole Amit P. Bhole Nima Saeidi Nima Saeidi Melody Liles Melody Liles Charles A. DiMarzio Charles A. DiMarzio Jeffrey W. Ruberti Jeffrey W. Ruberti Normalized edge intensity vs. time (minutes) for loaded (solid line) and unloaded (dashed line) ROIs shown in fig. 5. Public Library of Science 2010 loaded unloaded rois shown 2010-08-23 01:18:23 Figure https://plos.figshare.com/articles/figure/_Normalized_edge_intensity_vs_time_minutes_for_loaded_solid_line_and_unloaded_dashed_line_ROIs_shown_in_fig_5_/504703 <p>Typically, the noise threshold of the edge intensity algorithm is somewhere between R<sub>I</sub> [0.1, 0.2]. Note the large differences in degradation time between loaded and unloaded ROIs when R<sub>I</sub>  = 0.1 or R<sub>I</sub>  = 0.2 are used as end points (110 or 120 min. respectively).</p>