Treatment with enalapril and not diltiazem ameliorated progression of chronic kidney disease in rats, and normalized renal AT<sub>1</sub> receptor expression as measured with PET imaging - Fig 2
Basma Ismail
Rob A. deKemp
Etienne Croteau
Tayebeh Hadizad
Kevin D. Burns
Rob S. Beanlands
Jean N. DaSilva
10.1371/journal.pone.0177451.g002
https://plos.figshare.com/articles/figure/Treatment_with_enalapril_and_not_diltiazem_ameliorated_progression_of_chronic_kidney_disease_in_rats_and_normalized_renal_AT_sub_1_sub_receptor_expression_as_measured_with_PET_imaging_-_Fig_2/5025449
<p><b>Body weight data obtained weekly over 10 weeks (A), terminal left kidney weight for sham (N = 8), Nx (N = 8), NxE (N = 6) and NxD (N = 8) (B) and heart weight for sham (N = 8), Nx (N = 9), NxE (N = 9) and NxD (N = 8) (C) normalized to body weight at 18–20 weeks post-surgery.</b> Data are presented as mean±SD. * <i>p</i><0.05 vs sham, <sup>$</sup> <i>p</i><0.05 vs Nx, <sup>#</sup> <i>p</i><0.05 vs NxE (p<0.05).</p>
2017-05-19 17:28:13
CKD
blood flow
calcium channel blockers
1 R expression
kidney angiotensin II
diltiazem ameliorated progression
positron emission tomography
1 R levels
1 receptor expression
Nx
1 R changes
PET imaging ACE inhibitors
kidney disease
enalapril
systolic blood pressure