Supplementary Material for: Spironolactone for the Treatment of Acne: A 4-Year Retrospective Study Grandhi R. Alikhan A. 10.6084/m9.figshare.4970495.v1 https://karger.figshare.com/articles/journal_contribution/Supplementary_Material_for_Spironolactone_for_the_Treatment_of_Acne_A_4-Year_Retrospective_Study/4970495 <p>Prior studies have demonstrated that spironolactone is an effective second-line treatment option for postadolescent acne, but has notable side effects. Data are, however, limited. We therefore present a 4-year retrospective study evaluating 291.5 patient-years of spironolactone for the treatment of acne. Our results showed that 86% of patients improved on spironolactone therapy. Further, patients who improved showed minimal side effects, supporting recent evidence that spironolactone is a safe option for acne treatment with a low risk of short-term adverse effects such as hyperkalemia. It is suggested that our study encourages consideration of spironolactone for postadolescent acne.</p> 2017-05-04 12:33:43 Acne Female Postadolescent acne