TY - DATA T1 - Phytochemical composition and biological activities of Artemisia quettensis Podlech ethanolic extract PY - 2017/04/20 AU - Zahra Bagheri Farahani AU - Amir Mirzaie AU - Fatemeh Ashrafi AU - Maryam Rahimpour Hesari AU - Ali Chitgar AU - Hassan Noorbazargan AU - Arian Rahimi UR - https://tandf.figshare.com/articles/journal_contribution/Phytochemical_composition_and_biological_activities_of_i_Artemisia_quettensis_i_Podlech_ethanolic_extract/4892495 DO - 10.6084/m9.figshare.4892495.v1 L4 - https://ndownloader.figshare.com/files/8221646 KW - GC-MS KW - phytochemical composition KW - Artemisia quettensis Podlech KW - cytotoxicity N2 - The present study aim to investigate the phytochemical composition, antibacterial, antioxidant and anticancer activities of the ethanolic extract from aerial parts of Artemisia quettensis Podlech. The aerial part of A. quettensis Podlech extract was used for Gas chromatography–mass spectrometry (GC-MS) analysis, antioxidant, antibacterial and anticancer activities. GC/MS analysis of extract from this plant showed 23 major components and the most dominant components were acetic acid, [4-(1-hydroxy-1-methylethyl) cyclohex-1-enyl] methyl ester (13.88%), trans-Phytol (10.06%) and 2,6-Dimethyl-2,6-octadiene-1,8-diol diacetate (6.8%). The extract had significant antibacterial and anticancer effects. The highest percentage of antioxidant activity was 78.46% at 2 mg/mL concentration of extract. Moreover, the highest antibacterial effects of extract were against to gram-positive bacteria and the IC50 cell cytotoxicity value on HT29 cell line in 24 h, 48 h and 72 h were 31.54, 6.08 and 2.96 mg/mL, respectively. From this study, A. quettensis Podlech could be considered as a promising source for novel drug compounds. ER -