SUMO conjugates accumulate during productive EBV infection.
Jinlin Li
Simone Callegari
Maria G. Masucci
10.1371/journal.ppat.1006338.g001
https://plos.figshare.com/articles/figure/SUMO_conjugates_accumulate_during_productive_EBV_infection_/4883519
<p>Akata-Bx1 cells were harvested at the indicated times after induction by anti-IgG cross-linking and western blots were probed with antibodies to SUMO1 or SUMO2/3. (<b>A</b>) Induction of the productive cycle was confirmed in western blots probes with antibodies to the EBV transactivator BZLF1. Representative western blots illustrating the progressive accumulation of high molecular weight polypeptides reacting with antibodies to SUMO1 (<b>B</b>) and SUMO2/3 (<b>C</b>) antibodies; β-actin was used as loading control. * a longer exposure was required to visualize the free SUMO1.</p>
2017-04-17 17:53:21
SUMO-targeted ubiquitin ligase RNF 4.
virus Post-translational modification
SUMO conjugation machinery
Small Ubiquitin-like Modifier
inducible miR-BHRF 1-1 sponge
Epstein-Barr virus miR-BHRF 1-1 targets RNF 4
EBV miR-BHRF 1-1
miR-BHRF 1-1. Reconstitution
RNF 4 protein expression
RNF 4
virus cycle