Zheng, Yongbiao Xu, Li Wei, Liufeng Shi, Mianmian Zhang, Jiyan Huang, Jianzhong A Sphingosine-type cerebroside in <i>Clavicorona pyxidata</i> induce fruit body formation <p><i>Clavicorona pyxidata</i> is a wild edible and medicinal mushroom that is rich in bioactive natural products and has thus been extensively used as traditional medicine in China. The present study has determined that the organic crude extract prepared from a fermented culture of <i>C. pyxidata</i> imparted auto-inhibitory effects on mycelial growth and then induced the formation of fruiting bodies. By monitoring bioactivity, one compound was isolated via successive chromatography over silica gel, Sephadex LH-20, and Cl8-reversed phase silica gel and was identified as a known sphingosine-type cerebroside by nuclear magnetic resonance (NMR) and physicochemical data, namely, (4E, 8E)-N-D-2′-hydroxypalmitoyl-1-O-β-D-glucopyranosyl-9-methyl-4,8-sphingadienine. The application of this cerebroside at a concentration of 200 μg/disc paper resulted in the inhibition of aerial hyphal growth of <i>C. pyxidata.</i> The findings of the present study indicated that this <i>C. pyxidata</i> cerebroside is a fruiting body-inducing substance (FIS).</p> Clavicorona pyxidata;cerebroside;fruiting body formation 2017-03-28
    https://tandf.figshare.com/articles/journal_contribution/A_Sphingosine-type_cerebroside_in_i_Clavicorona_pyxidata_i_induce_fruit_body_formation/4793359
10.6084/m9.figshare.4793359