%0 Figure %A Cimini, Maria %A Cannatá, Antonio %A Pasquinelli, Gianandrea %A Rota, Marcello %A Goichberg, Polina %D 2017 %T Perivascular localization of the podoplanin-expressing cells. %U https://plos.figshare.com/articles/figure/Perivascular_localization_of_the_podoplanin-expressing_cells_/4782259 %R 10.1371/journal.pone.0173927.g004 %2 https://ndownloader.figshare.com/files/7867045 %K lymphatic network %K scar development %K artery ligation %K lymphatic vessel growth %K sham-operated counterparts %K lymphatic endothelium %K Podoplanin-carrying populations %K Podoplanin immunoreactivity %K infarcted adult heart %K infarcted myocardium %K podoplanin-containing cells %K infarcted heart %K mesenchymal markers %K infarcted hearts %K infarcted region %K scar formation %K VEGFR -3 %K podoplanin-expressing cell populations %K podoplanin-labeled cells %K spatiotemporal changes %K extracellular matrix deposits %K LYVE -1-negative cells %K fibrogenic responses %K VEGFR -2 content %K blood vessels %K podoplanin-positive cell compartment %K post-MI lymphangiogenesis %K mouse model %K wound granulation %K infarcted myocardium Cardiac lymphatic vasculature %K LYVE -1-positive lymphatic vessels %K pro-fibrotic cells %K master regulator %K PDGFR %K fibrotic area %K hematoendothelial epitope CD 34. %K podoplanin-presenting cells %K podoplanin-rich LYVE -1-negative multicellular assemblies %K Prox -1-positive %X

Thin cardiac sections were indirectly immunolabeled with podoplanin (red) and VEGFR-2 (green) antibodies. Nuclei, blue. Time after MI is indicated. Areas in rectangles are shown at a higher magnification in the adjacent images for each color channel and merged. Note the podoplanin-positive cells encircling the VEGFR-2-labeled BVs.

%I PLOS ONE