Additional file 6: of Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis Mohan Pammi Julia Cope Phillip Tarr Barbara Warner Ardythe Morrow Volker Mai Katherine Gregory J. Kroll Valerie McMurtry Michael Ferris Lars Engstrand Helene Lilja Emily Hollister James Versalovic Josef Neu 10.6084/m9.figshare.c.3712717_D6.v1 https://springernature.figshare.com/articles/figure/Additional_file_6_of_Intestinal_dysbiosis_in_preterm_infants_preceding_necrotizing_enterocolitis_a_systematic_review_and_meta-analysis/4736887 Alpha diversity trends over corrected gestational age alpha-diversity metrics (mean with SD) by corrected gestational age (weeks). Fig. A depicts observed species (in operational taxonomic units, OTUs) and Fig. B depicts Shannon diversity index (SDI) against corrected gestational age (CGA) in controls and in infants with necrotizing enterocolitis (NEC). Data is represented in box and whisker plots with median and whiskers representing 10–90th centiles. The results of a fitted negative binomial regression model showed that the number of species increased significantly with gestational age (p < 0.001), and NEC patients tended to have fewer species than controls after controlling for gestational age (p = 0.053). (TIF 39 kb) 2017-03-09 05:00:00 Microbiome Intestinal Preterm Neonate NEC 16S rRNA sequencing