10.1021/acs.joc.7b00073.s001 Yogesh Siddaraju Yogesh Siddaraju Kandikere Ramaiah Prabhu Kandikere Ramaiah Prabhu Iodine-Catalyzed Cross Dehydrogenative Coupling Reaction: Sulfenylation of Enaminones Using Dimethyl Sulfoxide as an Oxidant American Chemical Society 2017 dehydrogenative iodine metal-free reaction conditions reaction time Oxidant Synthesis Dimethyl Sulfoxide methodology enaminone method dimethyl sulfoxide Iodine-Catalyzed Cross Dehydrogenative heterocyclic thiols sulfenylation polyfunctionalized aminothioalkenes DMSO 2017-02-23 00:00:00 Journal contribution https://acs.figshare.com/articles/journal_contribution/Iodine-Catalyzed_Cross_Dehydrogenative_Coupling_Reaction_Sulfenylation_of_Enaminones_Using_Dimethyl_Sulfoxide_as_an_Oxidant/4731709 Synthesis of polyfunctionalized aminothioalkenes has been demonstrated using iodine as a catalyst (30 mol %) and dimethyl sulfoxide as an oxidant under metal-free reaction conditions. This methodology allows a facile sulfenylation of enaminones with a broad range of heterocyclic thiols and thiones using cross dehydrogenative coupling methods. In addition, this strategy is highly practical as it employs inexpensive and readily available iodine and DMSO with a short reaction time. The current methodology is one of the simplest methods and provides a straightforward approach to sulfenylation of enaminones via the cross dehydrogenative coupling method.