10.1021/acs.joc.7b00073.s001
Yogesh Siddaraju
Yogesh
Siddaraju
Kandikere Ramaiah Prabhu
Kandikere Ramaiah
Prabhu
Iodine-Catalyzed Cross
Dehydrogenative Coupling Reaction:
Sulfenylation of Enaminones Using Dimethyl Sulfoxide as an Oxidant
American Chemical Society
2017
dehydrogenative
iodine
metal-free reaction conditions
reaction time
Oxidant Synthesis
Dimethyl Sulfoxide
methodology
enaminone
method
dimethyl sulfoxide
Iodine-Catalyzed Cross Dehydrogenative
heterocyclic thiols
sulfenylation
polyfunctionalized aminothioalkenes
DMSO
2017-02-23 00:00:00
Journal contribution
https://acs.figshare.com/articles/journal_contribution/Iodine-Catalyzed_Cross_Dehydrogenative_Coupling_Reaction_Sulfenylation_of_Enaminones_Using_Dimethyl_Sulfoxide_as_an_Oxidant/4731709
Synthesis
of polyfunctionalized aminothioalkenes has been demonstrated
using iodine as a catalyst (30 mol %) and dimethyl sulfoxide as an
oxidant under metal-free reaction conditions. This methodology allows
a facile sulfenylation of enaminones with a broad range of heterocyclic
thiols and thiones using cross dehydrogenative coupling methods. In
addition, this strategy is highly practical as it employs inexpensive
and readily available iodine and DMSO with a short reaction time.
The current methodology is one of the simplest methods and provides
a straightforward approach to sulfenylation of enaminones via the
cross dehydrogenative coupling method.