10.1371/journal.pone.0017388.g006
Sabine Hagemann
Sabine
Hagemann
Oliver Heil
Oliver
Heil
Frank Lyko
Frank
Lyko
Bodo Brueckner
Bodo
Brueckner
Drug-induced demethylation patterns in HL60 myeloid leukemia cells.
Public Library of Science
2011
demethylation
patterns
hl60
myeloid
leukemia
2011-03-07 01:14:15
Figure
https://plos.figshare.com/articles/figure/_Drug_induced_demethylation_patterns_in_HL60_myeloid_leukemia_cells_/464455
<p>Methylation changes in HL60 cells treated for 24 h with AZA (A) or DAC (B); blue dots and numbers represent demethylated CGs (DB≤−0.2). C, D, Boxplots show demethylation efficiency indicated by DB values in AZA- and DAC-treated HCT116 cells dependent on CG association with CGIs; black lines denote medians, notches the standard errors, boxes the interquartile range, and whiskers the 2.5th and 97.5th percentiles. Boxplots show demethylation efficiencies as a function of degree of CG methylation in E, AZA- and F, DAC-treated HL60 cells. Methylation levels were grouped in 10% intervals from 0 to 100% methylation; black marks denote medians, boxes the interquartile range, and whiskers the 2.5th and 97.5th percentiles.</p>