10.1371/journal.pone.0017388.g006 Sabine Hagemann Sabine Hagemann Oliver Heil Oliver Heil Frank Lyko Frank Lyko Bodo Brueckner Bodo Brueckner Drug-induced demethylation patterns in HL60 myeloid leukemia cells. Public Library of Science 2011 demethylation patterns hl60 myeloid leukemia 2011-03-07 01:14:15 Figure https://plos.figshare.com/articles/figure/_Drug_induced_demethylation_patterns_in_HL60_myeloid_leukemia_cells_/464455 <p>Methylation changes in HL60 cells treated for 24 h with AZA (A) or DAC (B); blue dots and numbers represent demethylated CGs (DB≤−0.2). C, D, Boxplots show demethylation efficiency indicated by DB values in AZA- and DAC-treated HCT116 cells dependent on CG association with CGIs; black lines denote medians, notches the standard errors, boxes the interquartile range, and whiskers the 2.5th and 97.5th percentiles. Boxplots show demethylation efficiencies as a function of degree of CG methylation in E, AZA- and F, DAC-treated HL60 cells. Methylation levels were grouped in 10% intervals from 0 to 100% methylation; black marks denote medians, boxes the interquartile range, and whiskers the 2.5th and 97.5th percentiles.</p>