Supplementary Material for: Comparison of 55° Wide-Field Spectral Domain Optical Coherence Tomography and Conventional 30° Optical Coherence Tomography for the Assessment of Diabetic Macular Edema Munk M.R. Lincke J. Giannakaki-Zimmermann H. Ebneter A. Wolf S. Zinkernagel M.S. 10.6084/m9.figshare.4626175.v1 https://karger.figshare.com/articles/dataset/Supplementary_Material_for_Comparison_of_55_Wide-Field_Spectral_Domain_Optical_Coherence_Tomography_and_Conventional_30_Optical_Coherence_Tomography_for_the_Assessment_of_Diabetic_Macular_Edema/4626175 <p><b><i>Purpose:</i></b> To compare conventional 30° spectral domain optical coherence tomography (SD-OCT) with 55° wide-field SD-OCT for the assessment of diabetic macular edema (DME). <b><i>Methods:</i></b> This study included 50 DME patients. Both 55° and 30° SD-OCT was conducted. Two readers evaluated scans according to a standardized grading protocol. Intergrader agreement as well as agreement between 30° and 55° SD-OCT were assessed. <b><i>Results:</i></b> Intergrader agreement (κ) was strong and ranged from 0.79 to 1.0. Perfect interdevice agreement (κ = 1.0) was found for the detection of intra- and subretinal fluid. Excellent agreement (κ ≥ 0.9) was found for the presence of epiretinal membrane (κ = 0.92) and cotton-wool spots (κ = 0.92). A strong agreement was found for the presence of hard exudates (κ = 0.89) and microaneurysms (κ = 0.81). A moderate correlation was found for ellipsoid zone integrity (κ = 0.69) and configuration of the vitreomacular interface (VMI) (κ = 0.69). A weak agreement was found for retinal pigment epithelium atrophy (κ = 0.51) and external limiting membrane integrity (κ = 0.35). <b><i>Conclusion:</i></b> Wide-field OCT imaging may be beneficial for evaluating DME, particularly for assessing the VMI and the integrity of hyperreflective bands.</p> 2017-02-07 14:42:37 Wide-field imaging Diabetic macular edema Wide-field spectral domain optical coherence tomography Microaneurysms Vitreoretinal interface Macular edema Subretinal fluid Intraretinal fluid Hard exudates