Canestrari, Daniele Lancianesi, Stefano Badiola, Eider Strinna, Chiara Ibrahim, Hasim F. A. Adamo, Mauro Desulfurative Chlorination of Alkyl Phenyl Sulfides The chlorination of readily available secondary and tertiary alkyl phenyl sulfides using (dichloroiodo)­benzene (PhICl<sub>2</sub>) is reported. This mild and rapid nucleophilic chlorination is extended to sulfa-Michael derived sulfides, affording elimination-sensitive β-chloro carbonyl and nitro compounds in good yields. The chlorination of enantioenriched benzylic sulfides to the corresponding inverted chlorides proceeds with high stereospecificity, thus providing a formal entry into enantioenriched chloro-Michael adducts. A mechanism implying the formation of a dichloro-λ<sup>4</sup>-sulfurane intermediate is proposed. nitro compounds;Desulfurative Chlorination;enantioenriched benzylic sulfides;Alkyl Phenyl Sulfides;PhICl 2;enantioenriched chloro-Michael adducts;nucleophilic chlorination;chlorides proceeds;elimination-sensitive β- chloro carbonyl;alkyl phenyl sulfides;dichloro -λ 4 2017-02-02
    https://acs.figshare.com/articles/dataset/Desulfurative_Chlorination_of_Alkyl_Phenyl_Sulfides/4614733
10.1021/acs.orglett.7b00077.s002